Particulate Matter 2.5 Level Modulates Brachial Artery Flow-Mediated Dilation Response to Aerobic Exercise in Healthy Young Men

Particulate matter 2.5 (PM2.5) is an environmental pollutant linked with the risk of cardiovascular disease. Aerobic exercise performed in polluted environments may have fewer benefits because increased PM2.5 inhalation during exercise. However, vascular responses to aerobic high (HPM2.5) conditions remain unknown. This study aimed examine acute flow-mediated dilation (FMD) response moderate-intensity treadmill running HPM2.5 levels compared low (LPM2.5) healthy young males. Treadmill both and LPM2.5 was completed by nine subjects. Brachial artery FMD measured before after assess endothelial function. Indoor concentration significantly higher than (p < 0.001). Scaled but not = 0.03), baseline diameter only Baseline peak were smaller, time delayed pre-exercise intervention measurements 0.05). Therefore, exposure can counteract positive effect on function